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Dr. PCR BCR-ABL1 Major IS Detection Kit

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Dr. PCR BCR-ABL1 Major IS Detection Kit is a kit for highly sensitive detection and quantification of BCR-ABL1 (e13a2 and e14a2) and ABL1 transcripts by digital PCR technology using the LOAA™ dPCR system . Quantification of BCR-ABL1 and ABL1 transcripts is performed during the standard diagnosis and monitoring of chronic myeloid leukemia. Dr. PCR BCR-ABL1 Major IS Detection Kit in combination with LOAA™ dPCR allow precise quantification of transcripts without the use of quantitative standards. Kit components: Features and benefits: Absolute quantification — eliminates the need to use quantitative standards and construct standard curves High accuracy and precision of the analysis — ten times higher sensitivity, thanks to the digital PCR technology employed in the analysis Quick and easy workflow — the entire analysis is performed in three steps Automatic generation of a detailed patient report with the result expressed according to the International Scale %IS, MR Level and NCN (%) Workflow: Analytical characteristics: Limit of Detection (LoD): 0.0025 %IS (MR 4.6) Limit of Quantification (LoQ): 0.0025 %IS (MR 4.6) Dynamic range of quantification (e13a2, e14a2): 50 - 0.0025 %IS (MR 0.3 - MR 4.6)

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