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A New Breakthrough in Depression Diagnosis – Detecting MDD with a Simple Saliva or Blood Test

Discover how the new circRNA RT-PCR detection kit is revolutionizing early diagnosis of Major Depressive Disorder using non-invasive saliva or plasma samples. Learn how this innovative test works and why it's more accurate than traditional methods.

What Is circRNA ?

circRNA stands for circular RNA. It’s a type of molecule found in our body that plays an important role in regulating genes. Scientists have discovered that certain circRNA molecules change when someone has depression.

Using a special test called the circRNA RT-PCR Detection Kit , doctors can now measure these changes from a small sample of plasma (blood) or saliva (spit) . This makes it easier, faster, and less stressful for patients to get tested.

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Why This Test Matters ?

Traditional ways of diagnosing depression often rely on questionnaires, interviews, or self-reported symptoms. But now, we have a more scientific and objective method that supports mental health professionals in making better decisions.

Here’s what makes this test special :

  • Non-invasive – Just a saliva or blood sample
  • High accuracy – Up to 90% accuracy
  • High specificity – Over 95% specific for MDD
  • Early screening – Helps catch depression early
  • Therapy tracking – Can show how well treatment is working

  How Does the Test Work?

 The process is simple and fast :

  1. Sample Collection : Saliva or blood is collected.
  2. circRNA Extraction : The special RNA molecules are isolated.
  3. RT-PCR Testing : A lab machine reads the biomarker levels.
  4. Result Scoring : A score is calculated to show risk level.

The results are grouped into three categories :

Result Type

Score Range

Normal

Score < 20

Mild to Moderate

20 ≤ Score < 35

Severe

Score ≥ 35

Keep in mind : This test helps support diagnosis, but final evaluation should always be done by a trained professional like a doctor or psychologist.


Who Can Benefit ?

  • Pregnant and postpartum women.
  • IT professionals, pilots, military personnel, police officers, teachers , and others under high stress.
  • People with a family history of depression.
  • Those who may not recognize their own symptoms.

      

Why Early Detection Is Important ?

In Europe alone, 11% of people will suffer from MDD at some point — that’s much higher than the global average. Yet many don’t seek help due to stigma, lack of awareness, or misdiagnosis.

With this new test, we can :

Improve early screening

Reduce missed cases

Guide personalized treatments

Lower long-term costs and suffering

Circular RNAs in depression Biogenesis expression, and therapeutic potential

Discover The PDF for more !

Peripheral Blood Circular RNAs as aBiomarker for Major DepressiveDisorder and Prediction of PossiblePathways

 Peripheral Blood Circular RNAs as aBiomarker for Major DepressiveDisorder and Prediction of PossiblePathways

Looking Ahead !

As research continues, tools like the circRNA RT-PCR Detection Kit are helping us move toward a future where mental health is diagnosed as easily as physical health . This breakthrough brings hope to millions and marks a big step forward in the fight against depression.

If you or someone you know struggles with depression, remember: help is available, and now there are better tools than ever before to understand what’s going on inside the brain. Talk to a healthcare provider today and ask if a non-invasive depression test could be right for you.

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